Studies on Experimental Arteriosclerosis by Normolipidemic Method
نویسندگان
چکیده
منابع مشابه
Experimental Arteriosclerosis
Arteriosclerotic lesions have been produced in monkeys (Macaca nemestrina) by selective removal of the vascular endothelium with an intra-arterial balloon catheter. Immediately after de-endothelialization a platelet layer covers the denuded area. This thrombus is gradually removed and by 7 days the vessel appears to be largely reendothelialized. Beginning at day 4, smooth muscle cells undergo m...
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• The peculiarities of human arterio-atheroselerosis, its morphology, anatomical distribution, and variation with age, sex, diet, and social conditions, have made agreement difficult concerning its etiology. Observations in clinical medicine and in the laboratory suggest a relationship between vasoconstriction and arteriopathies. Essential hypertension, a disease of small arteries and arteriole...
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Transgenic mice expressing both human apolipoprotein (apo) B and human cholesteryl ester transfer protein (CETP) have been developed. When fed a normal mouse chow diet, the apoB/CETP double transgenic animals had threefold higher serum CETP activity than humans and had human apoB levels that were similar to those of normolipidemic humans. When compared with nontransgenic mice, the total serum c...
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1. Wright's method for the study of chemotaxis of leucocytes in vitro, slightly modified, has been found to be most satisfactory in the estimation of the degree of chemotaxis of various substances, because it is possible to make an exact quantitative determination of the leucocytes that have migrated from the blood clot and adhere to the surfaces containing the tested substance. 2. The calcium ...
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ژورنال
عنوان ژورنال: The Journal of Japan Atherosclerosis Society
سال: 1976
ISSN: 0386-2682,2185-8284
DOI: 10.5551/jat1973.4.3_185